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Our top choices for Southern Louisiana hotels

A spacious lobby with a staircase, seating area, and a reception desk.

1. DoubleTree by Hilton Hotel Lafayette

Lafayette

Allan Michael

$88 nightly

Nov 25 - Nov 26

Total with taxes and fees

A hotel room with two beds, a wooden headboard, a nightstand, a desk, a TV, and a large window with curtains.

2. Sonesta ES Suites Lafayette Airport Extended Stay

Lafayette

Heidi

$76 nightly

Nov 15 - Nov 16

Total with taxes and fees

3. La Quinta Inn & Suites by Wyndham Lafayette Oil Center

Lafayette

Katie

$82 nightly

Nov 29 - Nov 30

Total with taxes and fees

A modern lobby with grey upholstered armchairs, a round wooden ottoman, and a patterned rug.

4. Drury Inn & Suites Lafayette, LA

Lafayette

Gail

$117 nightly

Nov 15 - Nov 16

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a television, and a kitchenette.

5. Microtel Inn & Suites by Wyndham Scott/Lafayette

Scott

Patrick

$60 nightly

Nov 18 - Nov 19

Total with taxes and fees

A modern outdoor seating area with fire pit, chairs, and a covered patio.

6. Home2 Suites By Hilton Lafayette I-10

Lafayette

Kristina

$115 nightly

Nov 29 - Nov 30

Total with taxes and fees

A building with a stone facade, a covered entrance with a wooden arch, and a seating area with chairs.

7. Staybridge Suites Lafayette by IHG

Lafayette

Thierry

$105 nightly

Nov 22 - Nov 23

Total with taxes and fees

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase to an upper level.

8. Wingate by Wyndham Lafayette Airport

Lafayette

marvin

$76 nightly

Nov 22 - Nov 23

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a small kitchenette, and a bathroom with a toilet and sink.

9. Holiday Inn Express Hotel & Suites Lafayette by IHG

Lafayette

Claire

$65 nightly

Nov 29 - Nov 30

Total with taxes and fees

A modern reception area with a wooden reception desk, seating area with chairs and a table, and a glass door leading outside.

10. Candlewood Suites Lafayette - River Ranch by IHG

Lafayette

John

$71 nightly

Nov 15 - Nov 16

Total with taxes and fees

A swimming pool with a brick border, surrounded by a white fence and a wooden fence.

11. Howard Johnson by Wyndham Scott Lafayette

Scott

Tamika

$61 nightly

Nov 13 - Nov 14

Total with taxes and fees

A modern lobby with a reception desk, seating area, and a large plant.

12. Comfort Suites Oil Center

Lafayette

Cedric

$74 nightly

Nov 29 - Nov 30

Total with taxes and fees

A spacious lobby with a modern design, featuring a seating area, a fireplace, and a refreshment bar.

13. Hilton Garden Inn Lafayette/Cajundome

Lafayette

Shelby

$94 nightly

Nov 22 - Nov 23

Total with taxes and fees

An indoor swimming pool with clear water, surrounded by lounge chairs and a brick wall.

14. Holiday Inn & Suites Lafayette North by IHG

Lafayette

Melinda

$93 nightly

Nov 12 - Nov 13

Total with taxes and fees

A hotel lobby with a reception desk, seating area, and a large framed picture on the wall.

15. Comfort Inn & Suites Scott-West Lafayette

Scott

Sandra

$93 nightly

Dec 8 - Dec 9

Total with taxes and fees

A hotel reception area with a counter, a refrigerator stocked with beverages, and a snack bar with various food items.

16. Holiday Inn Express Hotel & Suites Scott - Lafayette West by IHG

Scott

Adriano

$109 nightly

Nov 19 - Nov 20

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a desk, a chair, a TV, and an air conditioning unit.

17. Best Western Rayne Inn

Rayne

tiffany

$84 nightly

Nov 15 - Nov 16

Total with taxes and fees

An outdoor patio area with a fire pit, seating, and a pergola with string lights.

18. TownePlace Suites by Marriott Lafayette South

Lafayette

Quentin

$101 nightly

Nov 15 - Nov 16

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a desk with a chair, and a view of a sunset through the window.

19. Days Inn by Wyndham Rayne/Crowley

Rayne

maureen

$66 nightly

Nov 11 - Nov 12

Total with taxes and fees

A large outdoor swimming pool with lounge chairs and palm trees, surrounded by houses.

20. Carriage House Hotel

River Ranch

Ben

$196 nightly

Dec 9 - Dec 10

Total with taxes and fees

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Vacation Rentals in Southern Louisiana

Vacation Home

A modern two-story building with a dark facade, large windows, and a central entrance with a small tree.

Enclave 1 Bedroom Suites

Lafayette

"We had a great stay here! Nice location and had everything we needed for a long weekend."

Cottage

A small, single-story house with a porch and a wooden fence.

Maison D'Memoire Bed & Breakfast Cottages

Rayne

"Delightful bed and breakfast venue. Real Southern charm and Lynn (the owner) was a fantastic host. Far exceeded our expectations and genuinely wished we could have stayed longer."

Vacation Home

A modern kitchen with grey cabinets, a central island with a sink, and a dining area with wicker chairs.

Enclave 3 Bedroom Luxury Homes

Lafayette

"Great Value! I highly recommend this property over hotels in the area."

Vacation Home

A hotel room with a bed, a desk, a chair, a clock, and a window with curtains.

Downtown Lafayette 4BR Home With Parking

Downtown Lafayette

"It is a beautiful home the house was"

Cottage

A cozy living room with a wooden ceiling, a dining area with a refrigerator, and a sofa with cushions.

Blue Dolphin Inn and Cottages

Grand Isle

"When we got there, it was so clean and it felt so spacious , 10/10 could go there again and get the same room 😊"

Cottage

A brick fireplace with a metal screen, surrounded by potted plants, under a wooden ceiling.

Shared BBQ Area & Pool! Cozy Home in Lake Charles

Lake Charles

"We had an incredible stay at this property (that includes our puppy). I highly recommend it!"

Cottage

A cozy room with a wooden ceiling, a gray sectional sofa, a wicker chair, and large windows offering views of the outdoors.

5 Mi to Downtown Morgan City: Waterfront Retreat

Morgan City

"Very comfortable inside lay out, and a wonderful place to sit outside and relax. "

Cottage

A bedroom with a bed, a television on a stand, a wardrobe, and a door leading to another room.

Walk to 1st Street: Family Home in Thibodaux!

Thibodaux

"This little home reminded me of my grandma's home when I was young. It has lots of old fashioned charm with modern decor. We were here for a birthday party so we didn't have an opportunity to enjoy downtown, but we did enjoy our stay. Next time we will bring our pup. He will love the nice backyard."

Cottage

A rustic dining area with a wooden table and bar stools, a stone wall, and a chandelier.

Dularge Grand Villa - Steps to Marina + Fishing!

Theriot

"The property was well maintained and more than enough for our group."

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Stay near popular Southern Louisiana attractions

A large tree with extensive branches and moss-covered trunks in a park.

University of Louisiana at Lafayette

8.6/10 (816 reviews)

Take a campus tour or just explore the area of University of Louisiana at Lafayette, during your trip to Lafayette. You can attend a sporting event while in the area.

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Learn more about Southern Louisiana

Explore the family-friendly area of Southern Louisiana—casinos, sports teams, and sights from Youngsville Sports Complex to Lake Peigneur.

See all hotels in Southern Louisiana

A sunset over a calm lake with a tree silhouette and a cloudy sky.

Top Southern Louisiana Hotel Reviews

Comfort Suites Oil Center

10/10 Excellent

"First ever stay in a Comfort Suites. Breakfast a little limited but overall a great stay in comfortable accomodation with clean laundry facilities and a small fitness room. Welcoming staff and spacious foyer and breakfast area. Very pleased with our short stay in Lafayette."

Sonesta ES Suites Lafayette Airport Extended Stay

8/10 Good

"What I needed was a getaway for the weekend and it gave me what I needed as far as comfort. Breakfast, well, if you can get any or wait for staff to replenish.. then it’s either you get it or not. Other than that my room was clean, spacious, and comfortable was totally at peace to do my work and enjoy a nights rest."